With a broad range of disseminated and subcutaneous tumor models characterized in NSG mice, and a scientific team that knows how to apply them, we can guide selection of the right tumor model for your Chimeric Antigen Receptor (CAR) T-cell study or other ACT study.
| Histotype | Model |
| Acute monocytic leukemia | MV-4-11-Luc-mCh-Puro (disseminated) THP1-Luc-mCh-Puro (disseminated) |
| Burkitt's lymphoma | Daudi-Luc-mCh-Puro (disseminated) Raji-Luc (SC/disseminated) |
| Lymphoblastic leukemia | NALM6-Luc-mCh-Puro (SC/disseminated) |
| Myeloid leukemia | Kasumi-3-Luc-mCh-Puro (disseminated) KG-1-Luc-mCh-Puro (disseminated) |
| Plasma cell myeloma | MM1.S-Luc-Neo (disseminated) MOLM-13 (disseminated) NCI-H929-Luc-mCh-Puro (disseminated) RPMI-8226 (SC) |
| Promyelocytic leukemia | HL-60-Luc-mCh-Puro (disseminated) |
| Histotype | Model |
| Bladder carcinoma | SW780 (SC) |
| Breast/mammary carcinoma | BT-474 (SC) HCC70 (SC) MDA-MB-231 (OT) MDA-MB-231-Luc-D3H2LN MDA-MB-468 (SC) ZR-75-1 (SC) |
| Gastric carcinoma | NCI-N87 (SC) SNU-5 (SC) |
| Glioblastoma | U-251-Luc-mCh-Puro (SC/intracranial) |
| Hepatocellular carcinoma | Hep 3B2.1-7 (SC) Hep G2 (SC) |
| Hypopharyngeal squamous cell carcinoma | FaDu |
| Lung cancer: Non-small cell lung carcinoma | A549 (SC) Calu-3 NCI-H1299 (SC) NCI-H1703 (SC) NCI-H1975 (SC) NCI-H1975-Luc (SC) |
| Lung cancer: Small cell lung carcinoma | DMS-114 (SC) NCI-H446 (SC) NCI-H82 (SC) SHP-77 (SC) |
| Melanoma | A-375 (SC) SK-MEL-28 (SC) |
| Ovarian carcinoma | OV-90 (SC) OVCAR-8-Luc-mCh-Puro (SC/IP) PA-1 (SC) SK-OV-3 (SC) SK-OV-3-Luc-D3 (IP) |
| Pancreatic ductal adenocarcinoma | BxPc-3 (SC) MIA PaCa-2 (SC) |
| Prostate carcinoma | 22Rv1 (SC) LNCaP clone FGC (SC) PC-3 (SC) PC-3M-Luc-C6 (SC) |
