Cardiovascular Safety
- Ion channels (hERG, CaV1.2, NaV1.5 peak, NaV1.5 late)
- Human stem cell derived cardiomyocyte (action potential, contractility, intracellular calcium)
Custom in vitro assays and New Approach Methodologies (NAMs) with flexible design options inform decisions to advance your molecule to in vivo testing during early-stage drug development.
The world’s demand for safe products is growing, and the demand for innovative in vitro models is growing along with it. We have built a reputation for quickly and effectively responding to changing regulatory requirements as well as the evolving industry sentiments regarding product testing. Our researchers have a keen focus on bringing you more in in vitro alternatives and automation driven study solutions.
As you progress in your development journey, let us be your partner. We offer custom in vitro assays and New Approach Methodologies (NAMs) with flexible design options and work with you to determine which mechanistic and biological endpoints are most relevant. Our scientists are at the cutting edge of in vitro alternative method development and are frequently requested to participate in regulatory working groups and testing/validation programs.