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More than 100 scientists offer genetic tox services from our global centers of excellence
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State-of-the-art GLP study designs based on the most up-to-date guidelines
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Broad experience with many non-standard investigative assays
Regulatory assays
Review common regulatory assays required for GLP studies.
Screening assays
Take a faster approach and explore common screening assays that can help predict GLP-compliant studies.
Multi-endpoint assays
Contact us to explore multi-end point studies such as the integration of micronucleus assessments into repeat dose toxicity studies; the transgenic rodent mutation assay; or the combination of acute micronucleus and comet assay.
Why partner with Labcorp for your genetic toxicology studies
Reach your destination
Evaluating the genetic toxicity of a drug or chemical is a journey. Make smarter decisions faster with unique perspectives that save you time and resources. Our team helps you navigate the draft ICH M7 and new OECD guidelines. We deliver solutions such as centromere probing of micronuclei, 3D skin models, as well as in vivo comet and transgenic Muta™Mouse assays. These unique solutions enable us to help you gain genetic insights about your molecule that most other CROs can’t help you obtain.
Experience global solutions customized to your needs
Did you know that you can get our globally recognized genetic toxicology services from any of our world-class facilities? We have purpose-built genetic toxicology centers of excellence in Greenfield, IN, Harrogate, UK and Porcheville, France. You partner with a team of more than 100 genetic toxicology specialists, including many study directors with more than 20 years of experience in the field. Working with you, we create a clearer picture of any potential genotoxic risk.
Consider some of our standard battery of tests that meet ICH or OECD requirements:
In vitro assays
- Ames, mammalian gene mutation (mouse lymphoma assay)
- Chromosome aberration (human lymphocytes and CHO cells)
- Micronucleus (human lymphocytes and cell lines)
In vivo assays
- Rodent bone marrow micronucleus and chromosome aberrations
- Comet and combination (micronucleus and Comet)
Discover uncommon assays for uncommon insights
We specialize in non-standard assays too — enabling you to better understand issues that arise during the discovery or development phases. These investigative assays give you a quick way to address and resolve issues with lead candidates as you move through the development journey.
Gain an experienced team to help you assess genetic risk
Whether you need assays to meet regulatory requirements, affordable screening studies or highly efficient multi-endpoint assays, you partner with a large and diverse team of toxicologists who specialize in assessing genetic risk.